CDKL5 Polyclonal Antibody, 50ul Cell Function Analysis Tyrosine kinase growth factor receptors

Tyrosine kinase growth factor receptors activate mitogen-activated protein kinases which then translocate into the nucleus and phosphorylate nuclear targets

liver and brain but not in other tissues

The encoded protein plays a role in chondrocyte proliferation and differentiation

through which this receptor induces the activation of NF-kappa B and MAPK8/JNK

PTM:Phosphorylated on serine residues by MAPK kinases upon insulin stimulation

CDKL5 Polyclonal Antibody, 50ul Cell Function Analysis Tyrosine kinase growth factor receptorsThis gene is a member of Ser Thr protein kinase family and encodes a phosphorylated protein with protein kinase activity. Mutations in this gene have been associated with X linked infantile spasm syndrome (ISSX), also known as X linked West syndrome, and Rett syndrome (RTT). Alternate transcriptional splice variants have been characterized.